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  • A Simplified Approach to Bioanalytical Sample Preparation

    Wednesday, April 08, 2015
    Application Note
    Erica Pike
    The complexity of biological samples can pose challenges to downstream analysis in the pharmaceutical industry. Bioanalytical and drug metabolism and pharmacokinetics (DMPK) groups often work with ... read more

  • Transitioning From HPLC to UHPLC of Proteins

    Wednesday, March 09, 2016
    Application Note
    Robert L. Stevenson, Ph.D.
    Since the introduction of ACQUITY UPLC (Ultra Performance Liquid Chromatography) by Waters (Milford, Mass.) over a decade ago, there has been increased interest in the effects of high pressure on ... read more

  • Sample Prep for LC, GC, and SFC at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    At Pittcon® 2013, sample prep stood out as a major focus, perhaps because of the few advances in chromatography instrumentation. In addition, some sample preparation is spilling over into other ... read more

  • Capillary-Channeled Polymer (C-CP) Fibers: A Novel Platform for Liquid-Phase Separations

    Wednesday, June 01, 2005
    Technical Article
    Dwella M. Nelson Rayman D. Stanelle Phil Brown R. Kenneth Marcus
    In spite of its relative maturity as a group of analytical methods, the field of liquid chromatography continues to evolve with regard to the development of new stationary phases that may provide ... read more

  • Using FAIMS to Increase Selectivity for LC-MS Analyses

    Wednesday, June 01, 2005
    Technical Article
    Roger Guevremont Beata Kolakowski
    In the development of many LC-MS methods, interferences are commonplace. In an environment in which data must stand up to rigorous scrutiny, such as in the pharmaceutical industry, selectivity of ... read more
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