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  • A Simplified Approach to Bioanalytical Sample Preparation

    Wednesday, April 08, 2015
    Application Note
    Erica Pike
    The complexity of biological samples can pose challenges to downstream analysis in the pharmaceutical industry. Bioanalytical and drug metabolism and pharmacokinetics (DMPK) groups often work with ... read more

  • Transitioning From HPLC to UHPLC of Proteins

    Wednesday, March 09, 2016
    Application Note
    Robert L. Stevenson, Ph.D.
    Since the introduction of ACQUITY UPLC (Ultra Performance Liquid Chromatography) by Waters (Milford, Mass.) over a decade ago, there has been increased interest in the effects of high pressure on ... read more

  • Automated Cell Staining in Drug Discovery

    Tuesday, April 09, 2013
    Application Note
    Amy Yoder Li Liu
    Cell and molecular biology become more integral pieces of the modern drug discovery process on a seemingly daily basis. Monitoring the interaction of cells and internal cellular activity provides ... read more

  • Putting the “More” in Morphology: Part 1

    Wednesday, April 10, 2013
    Technical Article
    Barbara Foster
    Segmentation, the ability to define the unique features in a region of interest, has always been the greatest challenge in image analysis and quantitation. A new suite of tools, available from ... read more

  • Product Intelligence: Considerations for Selecting Flow Cytometers

    Monday, February 25, 2013
    Technical Article
    Caitlin Smith
    Apoptosis, cell proliferation, cell cycle regulation, and immunophenotyping are some of the areas in which flow cytometers find application. Researchers have many options to consider when shopping for... read more

  • Automated Liquid Handling Robots: Bridging the Gap Between Nanoliter Liquid Handling and Larger ...

    Wednesday, March 06, 2013
    Application Note
    Wendy Gaisford
    The introduction of automated nanoliter volume liquid handling instrumentation has revolutionized work flows, reducing the tedium of manual pipetting and the potential for manual error. In addition, ... read more

  • Sample Prep for LC, GC, and SFC at Pittcon® 2013

    Friday, May 10, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    At Pittcon® 2013, sample prep stood out as a major focus, perhaps because of the few advances in chromatography instrumentation. In addition, some sample preparation is spilling over into other ... read more

  • Flow Cytometry Applied to Plant Reproductive Biology

    Thursday, November 07, 2013
    Application Note
    Diego H. Hojsgaard Elmar Herbig
    Understanding how biodiversity is distributed in nature and how it is impacted by human activities has become crucial for nature conservation. read more

  • Automated Assays and More at SLAS 2013 and HCA 2013

    Wednesday, February 06, 2013
    Technical Article
    Robert L. Stevenson, Ph.D.
    The second annual meeting of the Society for Laboratory Automation and Screening (SLAS 2013), held January 12–16, attracted 3800 scientists and engineers to the Gaylord Hotel in Orlando, FL for an ... read more

  • Detection of siRNA-Mediated Gene Modulation Using RNA Detection Probes

    Monday, May 20, 2013
    Application Note
    Don Weldon Grace Johnston
    To study the function of genes and biological pathways, researchers often use techniques such as RNA interference (RNAi) to modify gene expression. In RNAi experiments, it is important to determine ... read more

  • Measurement of IL-6 RNA Levels in Live Cells

    Wednesday, July 10, 2013
    Application Note
    Shobana Vaidyanathan
    Infections and tissue damage lead to acute inflammatory responses, orchestrated by the release of cytokines from macrophages and mast cells, as well as endothelium and tumor cells. Tumor necrosis ... read more
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