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Title
Increasing Quality Control Testing Efficiency with Compliant-Ready SOP Digital Forms
Monday, March 01, 2010
Thomas Schmidt
Wolfgang Lemmerz
Chris Stumpf
A survey of pharmaceutical team leaders conducted in 2005 found that the three biggest challenges facing pharmaceutical manufacturing were standard operating procedures (SOPs) and training, quality ...
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The Missing Link Between HPLC and UPLC Technology
Monday, February 01, 2010
William Foley
Beth Gildea
Thomas E. Wheat
Having proven its performance and reliability under extremely rigorous conditions for the most demanding applications, UPLC technology has brought routine benefits to increasing numbers of scientists,...
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The Use of Gel Permeation-Chromatography for the Cleanup of Samples in the Analytical Laboratory
Monday, February 01, 2010
Wendy Rasmussen
Gel permeation chromatography (GPC) is a subset of a very common technique called size exclusion chromatography (SEC), which involves the separation of molecules by their hydrodynamic volume in ...
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The Future of Rapid On-Line Measurement
Monday, February 01, 2010
Aubrey Lambert
Fiber optic technology has already radically altered the telecommunications field, by carrying highly multiplexed data at great speeds over vast distances. Now these capabilities have been packaged ...
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Choosing Solvent Packaging to Increase Laboratory Efficiency and Quality While Reducing Waste Disposal Costs
Monday, November 01, 2010
Jim Westra
Qing Ping Han
Paul McCoy
Rosanne Isom
Mark Hayward
Laboratory scientists have a finite number of work hours to accomplish their required research. The annual cost of a scientist and laboratory space for this research in today’s modern, instrument ...
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High-Precision, High-Sensitivity Measurements of Lead and Cadmium in Honey by GFAAS
Monday, March 01, 2010
Zhi-Gang Ouyang
Zhong-Lan Chen
Ying Wu
Honey is a natural substance produced in honeycombs by honeybees under special conditions. For centuries, honey has often been referred to as nature’s medicine. It is known to help heal bronchial ...
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Supporting Pharmaceutical Cleaning Validation With TOC and UV-VIS Spectrophotometric Analysis
Friday, October 01, 2010
Richard H. Clifford
Quality control and product safety are paramount in the manufacture of pharmaceutical products. Therefore, it is essential that substances other than those approved for a product are not included with...
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A Novel Method for Measuring Zeta Potential of High-Concentration, Low-Volume Protein Samples
Friday, October 01, 2010
Fraser McNeil-Watson
Michael Kaszuba
Understanding and controlling the characteristics of proteins in solution is fundamental to predicting their aggregation behavior and determining appropriate conditions for storage, crystallization, ...
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Applications of Vibrational Circular Dichroism for Determining Absolute Configuration in Early Drug Discovery
Friday, October 01, 2010
Feng Qiu
Yingru Zhang
Janet Caceres-Cortes
Michael D. Reily
Chirality is an intrinsic property of living matter, and many biological molecules exhibit a preference for one enantiomer over another. As such, chirality has been introduced into more than half of ...
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Direct Determination of Trace Elements in Solid Samples by DC Arc With Emphasis on the Analysis of High-Purity Copper
Friday, January 01, 2010
Maura Mahar
Garry Kunselman
Peter Brown
Paul Dalager
Peter Perzl
Fast, direct, quantitative elemental analyses of solids that are difficult to digest are hallmarks of the DC Arc technique. The earliest DC Arc instruments relied on photographic plate detectors. ...
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Confidence Up Close
Friday, January 01, 2010
Aubrey Lambert
The combined pressures of continuing miniaturization, higher packing densities, and rigorous quality assurance means that the physical size of particles capable of adversely affecting industrial ...
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Integrating Informatics and High-Content Screening to Find a Cure for Spinal Cord Injury: Selecting a LIMS for CNS Regeneration
Friday, January 01, 2010
Vance Lemmon
William Buchser
Don Crossett
The Miami Project to Cure Paralysis, part of the University of Miami Miller School of Medicine, includes a laboratory devoted to high-content screening (HCS) of neurons. The laboratory is run by Vance...
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Use of Rotational Vane Rheometry to Solve Practical Problems
Saturday, August 01, 2009
David J. Moonay
Rheology is the study of the deformation of matter. A common definition is that rheology is the study of flow. Viscometry, in particular, is the measurement of viscosity or the resistance to flow. ...
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Sediment Standard Reference Materials
Saturday, August 01, 2009
Michele Schantz
Rolf Zeisler
The National Institute of Standards and Technology (NIST, Gaithersburg, MD) issued a new series of Standard Reference Materials® (SRMs) targeting the ever-increasing list of potentially toxic ...
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A Novel Approach to Particle Size Measurement in the Single-Nanometer Range
Saturday, August 01, 2009
Yanyin Yang
Robert H. Clifford
Gilbert Vial
Haruo Shimaoka
Nanotechnology is pervasive, as evidenced by the abundance of information found in the latest scientific journals. What is nanotechnology? According to the National Nanotechnology Initiative, “a ...
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Automating Sample Preparation in the Metals Laboratory
Saturday, August 01, 2009
Joe Boyd
Preparing samples for analysis is an extremely time-consuming task. In fact, sample preparation steps can easily take up more time in the laboratory than the actual analysis. With autosamplers on ...
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ICP Spectrometry Coupled With a Separate Sampling and Excitation Accessory for Rapid Analysis of Impurities in Silver
Wednesday, July 01, 2009
George Buchbinder
Nikolai Verblyudov
Andrew Clavering
Silver is one of the oldest metals known to humanity and is still very important in minting, jewelry, and industry. Silver can be obtained from pure deposits and ores and, like other precious metals, ...
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Using a Purge-and-Trap Concentrator for Newly Proposed U.S. EPA Method 524.3
Thursday, June 18, 2009
Teri Dattilio
Purge-and-trap (P&T) concentration along with GC analysis is a widely used method for the detection of volatile organic compounds (VOCs). This methodology was developed to achieve the high sensitivity...
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Determination of Metal Impurities Present in Solar-Grade Bulk Silicon by ORS-ICP-MS
Thursday, June 18, 2009
Junichi Takahashi
Research into alternative energy sources is accelerating, with one of the most dynamic areas of interest being the development of devices to harness solar energy. Some industry experts, including the ...
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A Versatile Substrate Coated With Silver Nanoparticles for Surface-Enhanced Vibrational Spectroscopy
Thursday, June 18, 2009
Beng Guat Ooi
Lijie Zhao
Ngee-Sing Chong
Both infrared and Raman spectroscopic techniques are useful for probing the structure of complex molecules. However, they are typically not as sensitive as mass spectrometric techniques and hence have...
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