Application Notes

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Bottle Liquid–Liquid Extraction Update: In Situ Water Sample Preparation
Tuesday, January 21, 2014

As first described in Ref. 1, an alternative liquid–liquid extraction technique was originally conceived, born, and cultivated in an environmental lab setting to enable holding time obligations to be ... Read More
Ultrafast Confocal Raman Imaging - Application Examples
Monday, January 27, 2014

Using the Ultrafast Confocal Raman Imaging Option, a single Raman spectrum can be acquired in as few as 760 µsec. A wide variety of samples can be analyzed with the Ultrafast Confocal Raman Imaging ... Read More
Ultrasensitive 3D Confocal Raman Imaging
Monday, January 27, 2014

This article describes integration of a Raman spectrometer and a state-of-the-art confocal microscope to achieve ultrafast Raman imaging. The alpha300 R ultrafast confocal Raman imaging system was ... Read More
Imaging of Graphene with Confocal Raman and Atomic Force Microscopy (AFM)
Monday, January 27, 2014

Graphene is a two-dimensional material and as such is applicable in a wide variety of fields. Graphene characterization requires the use of a measurement tool that is nondestructive. An effective tool... Read More
Automated Colony Counting: A Critical Requirement for Advanced Cancer Research
Monday, February 10, 2014
Michael Rau
The colony counting method has long been recognized as the primary method for measuring the effects of radiation, chemotherapeutic drugs, and other agents on cell viability. Read More
Electronic Pipetting: The Call for Innovation
Thursday, February 27, 2014
Paula Heimler
Take a close look around most laboratories and you will find an old, barely used fixture. No one knows who ordered it or who it belongs to. It is yellowed, dusty, and top heavy, with a small keyboard ... Read More
Comparative Analysis of Antinuclear Antibody and Antinuclear Antibody Spectrum
Friday, February 28, 2014
Cui Kong Jianwei Zhou Jinsong Sun Aihua Shen Qin Song Xinke Chen Li Li
The occurrence of autoimmune disease (AID) has increased 3–5% and has had a significant impact on human health. The detection of serum antinuclear antibody (ANA) is beginning to receive more attention... Read More
Ensuring Data Integrity in Dropping Point Determination
Wednesday, March 12, 2014
Hans-Joachim Muhr
Softening and dropping point determination are established analytical tests that provide quality control for petrochemical products such as lubricating grease. However, to be accurate and comparable, ... Read More
Single-Cell RNA Detection to Identify Cell Subpopulations in Heterogeneous Mixtures
Tuesday, March 25, 2014
Don Weldon Victor Koong Alex Ko Yuko Williams Laura White
Traditional RNA detection methods, which analyze RNA levels in lysed, permeabilized, or fixed cell samples, make it challenging to understand the role of one gene in the context of a tissue, organ, or... Read More
How Electronic Laboratory Notebooks Aid in the Development of Bioanalytical Assays for Large Molecule Detection by LC/MS
Wednesday, April 16, 2014
Laura Swift
The use of electronic laboratory notebooks (ELNs) is becoming more popular among research and development (R&D) organizations. These electronic platforms optimize workflow and expedite data analysis ... Read More
Meeting the Challenge of Biological Changes Postsampling
Friday, May 16, 2014
Marcus Söderquist
Understanding the role of proteins, peptides, and their post-translational modifications, e.g., phosphorylations, in normal and diseased biological samples is crucial to elucidate in vivo biological ... Read More
DNA Modification in Obese Persons: Detection and Estimation of Carboxymethyl-2’- Deoxyadenosine in Human Urine and DNA
Monday, September 01, 2014
Zeenat Ara Lila Dawnn Flowers Morgan Tubman-Jackson
Genetics, obesity, and lack of exercise play a vital role in the development of diabetes. Almost 80% of people with Type 2 diabetes are overweight. Read More
Determination of Sulfonamides in Chicken Liver by Capillary Electrophoresis with an In-Column Fiber-Optic LED-Induced Fluorescence Detector
Tuesday, September 30, 2014
Lihong Guo Dan Xiao Martin M.F. Choi
Sulfonamides (SAs) are a class of synthetic antimicrobial compounds with a broad spectrum. As shown in Figure 1, they all contain the same chemical structure of an unsubstituted amino on a benzene ... Read More
Role of Cetyltrimethylammonium Bromide in Preparing Porous In-TiO₂ Photocatalytic Material
Friday, January 02, 2015
Wenjie Zhang Xiaobei Pei Jinlei Chen
The application of TiO₂ as the main photocatalyst on degradation of organic pollutants has been widely investigated. Metal ion doping can retard recombination of photogenerated electron-hole pairs in ... Read More
Determination of Palladium in Water and Geological Samples by Flame Atomic Absorption Spectrophotometry
Thursday, November 28, 2013
Dong Zhang Qian-Wu Wang
The precious metal palladium has been widely applied in the electronics, aerospace, chemical, metallurgy, automobile engines, and pharmaceutical industries due to its corrosion resistance, oxidation ... Read More
Characterization of Functionalized Polyolefins by High-Temperature Two-Dimensional Liquid Chromatography
Friday, January 28, 2011
Anton Ginzburg Tibor Macko Robert Brull
Functionalized polyolefins, such as copolymers of ethylene vinyl acetate (EVA), are a commercially important polymer commodity. Read More
Quality Verification of Incoming Liquid Raw Materials by FTIR Spectroscopy
Friday, January 28, 2011
Frank Higgins Alan Rein
The requirement to ensure the quality of incoming raw materials as well as finished products in the food, drug, and cosmetics industries is crucial, and FTIR spectroscopy is widely used for this ... Read More
Controlling Transformer Aging With Interfacial Instrumentation and Viscometers
Friday, January 28, 2011
Armin Hofmann
High-power transformers are some of the most important elements in the supply of energy. Read More
Determination of Mercury in Slag and Cement Using a Mercury Analyzer
Friday, January 28, 2011
Sang-Ho Nam Yu-Na Kim Jin-Su Na Keun-Hyeok Yang
Mercury is one of the most toxic elements in the environment. Humans are exposed to mercury through the inhalation of mercury vapor, ingestion of drinking water, and consumption of fish. Read More
Improving FTIR Operation With a Contaminant Analysis Program
Wednesday, September 01, 2010
John Monti
Spectrum search (library search) is a procedure often used in contaminant analysis. It consists of using the search function included in Fourier transform infrared (FTIR) software or specialized ... Read More