Application Notes

Sort

Drying of Problematic Purification Samples by Lyophilization in a Centrifugal Evaporator
Monday, June 13, 2011
Induka Abeysena Rob Darrington
Lyophilization is often the preferred method of sample drying because a high level of dryness is achieved with low residual solvent levels, and because of the light, powdery, “fluffy” finish of the ... Read More
Cell-Based Biosensors: A Quartz Crystal Microbalance Approach to Membrane Protein Interaction Studies
Monday, June 13, 2011
Karin Elovsson Zhichao Pei Teodor Aastrup
Drug development today is a time-consuming and expensive business, with costs reaching over $1 billion from drug discovery to market. Read More
Achieving Traceable Flow Measurement and Control of Gases in Scientific Research and Biopharmaceutical Systems
Monday, June 13, 2011
Larry Gallagher
As more research in science and pharmaceutical development is dependent on understanding and controlling the growth of cells and complex biochemical reactions, accurate and traceable measurement and ... Read More
Designing Safety Into Site-Wide Gas Distribution Systems
Tuesday, June 14, 2011
Mike Marone Ron Geib
When setting up a gas distribution system in a laboratory or any other type of facility, the safety of all personnel must be taken into consideration. Read More
LIMS and DNA Analysis in the Forensics Laboratory
Tuesday, February 17, 2015
Robin Gall
Laboratory information management systems (LIMS) are valuable tools in the forensics laboratory, streamlining the documentation and management of evidence including sample accession, extraction, ... Read More
Pure Water: The Most Essential Laboratory Element
Friday, January 16, 2015
Frank Gatzemeyer
Both vital and versatile, water is used in all laboratories, in preparing media, buffers and additives and for heating, cooling, cleaning and rinsing. Read More
What Does Your Particle Size Data Mean?
Thursday, February 19, 2015
Paul Kippax Deborah Huck-Jones
Laser diffraction is a mature technology with extensive capabilities. Highly automated and easy to use, modern laser diffraction systems efficiently meet the requirements for particle size data ... Read More
Use of Microcalorimetry to Study Protein Stability
Monday, February 16, 2015
Rémi André Link Brown
Differential scanning calorimetry (DSC) is used in the pharmaceutical, polymer and biotechnology industries to study the effect of temperature on a variety of solids or liquids, including those that ... Read More
High-Throughput Tools for Optimizing Drug Nanosuspensions
Thursday, February 19, 2015
Dennis H. Leung Timothy Rhodes Annette Bak
Inadequate absorption and bioavailability often make it difficult to deliver the drug to the target in vivo and pose significant challenges to the discovery and development of new drugs. A number of ... Read More
Exclusive Interview With SciAps Inc. CEO and co-Founder Don Sackett
Friday, January 31, 2014
Maria Stone
Q: Could you please describe your role at SciAps? A: I am the co-founder of the business and also the Chief Executive Officer (CEO). I lead the setting up of the distribution, the marketing, as well ... Read More
Advanced Electron Paramagnetic Resonance Spectroscopy for the Identification of Irradiated Food
Friday, January 31, 2014
Joong-Ho Kwon Hafiz Muhammad Shahbaz Jae-Jun Ahn
Electron paramagnetic resonance spectroscopy (ESR) is a spectroscopic technique that permits the detection of unpaired electrons originating from radicals, including those induced by irradiation or ... Read More
Using Micro-XRF to Quantify Thickness and Composition of Thin-Film Solar Cells
Wednesday, February 05, 2014
Andrew Lee
Thin-film solar cells (TFSCs) have developed into a highly efficient source of energy in solar cell technology, due to the reduction in semiconductor material required compared to traditional solar ... Read More
How Solid-Phase Extraction Affects Challenges in Bioanalysis
Wednesday, February 05, 2014
Mike Oliver Tim Liddicoat Ken Meadows
Modern bioanalytical laboratories are tasked with providing high-quality analytical results from complex biological samples in a high-throughput environment. These needs have to be balanced with the ... Read More
How Lab Informatics Technologies Help Meet Evolving Healthcare Needs
Wednesday, February 05, 2014
Shooki Grasiani Don Koch Randy Hice
As U.S. healthcare providers (HCPs) navigate a changing healthcare climate, diagnostic laboratories are playing an increasingly important role in helping them prevent medical errors, lower ... Read More
Seeing Molecular Interactions of Large Complexes by Cryo Electron Microscopy at Atomic Resolution
Thursday, February 06, 2014
Laurie J. Wang Z.H. Zhou
Suppose one has never seen an automobile and is asked to perform the simple task—while blindfolded—of adding gasoline to the car and checking its oil. A task like this is impossible to perform until ... Read More
Direct Sample Analysis/Time-of-Flight Mass Spectrometry
Thursday, February 06, 2014
Avinash Dalmia Andrew Tyler
There have been many developments in mass spectrometry ionization techniques in recent years, enabling the investigation of diverse sample types across the molecular weight range. Some of these ... Read More
Material Characterization With Complete Compositional Analysis Using Thermogravimetry
Wednesday, January 16, 2013
Matthias Wagner Michael R. Zemo
Consistent high performance demanded from modern materials has been a topic of discussion for both technical and business individuals for many years. The globalization of the supply and ... Read More
Automated On-Line Extraction and Analysis of Dried Blood Spot Cards
Wednesday, January 16, 2013
Lester Taylor Na Pi Parra Doug McIntyre
The use of dried blood spot cards for screening neonates for metabolic and genetic disorders was conceived and proposed almost 50 years ago. Since then, newborns in many countries have had their ... Read More
Recent Developments in Sulfur Analysis
Thursday, January 17, 2013
Scott Fess
Environmental concerns to limit and minimize sulfur in crude oil and petroleum fuels are continuing to spread to many regions of the world, requiring new standard test methods and modern ... Read More
A Look Into the Petrochemicals Industry
Tuesday, January 10, 2012
Mukta M. Shukla Ashok K. Shukla
Petrochemicals are a vital part of our lives, and it is hard to imagine modern existence without them. Read More