Application Notes

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Next-Generation Sequencing for Disease Biomarkers
Monday, December 15, 2014
Darren Lee
Next-generation sequencing (NGS) is beginning to provide powerful insights into genetic mutations and molecular networks underlying disease for a broad set of genes. NGS technologies promise to ... Read More
Analytical Method Development in the Quality by Design Framework
Tuesday, December 16, 2014
Torgny Fornstedt Dennis Åsberg Jörgen Samuelsson Anders Karlsson Krzysztof Kaczmarski
The development of analytical methods in the Quality by Design (QbD) framework is currently gaining great momentum in the pharmaceutical industry. Presented here is a case study in which a ... Read More
Electrochemical Determination of Acetaminophen Using Gold Nanoparticles–Multiwall Carbon Nanotubes Modified Glassy Carbon Electrode
Monday, December 15, 2014
Youyuan Peng Zhifu Zheng
Since their discovery in 1991, carbon nanotubes (CNTs) have been extensively studied for use in emitting devices, energy storage, sensor field, and biological and biomedical applications. Read More
How Do You Evaluate “Flowability”? Buttermilk Ranch vs Blue Cheese
Monday, November 24, 2014
Robert G. McGregor Eric Chiang Stephanie Shepard
A common request from food manufacturers is to come up with a faster and more definitive test for flowability of salad dressings. Read More
Interview with Udit Batra, President and CEO, EMD Millipore
Tuesday, November 25, 2014
Emilia Raszkiewicz
ER: I am aware that there have been many exciting business developments within EMD Millipore in the past year, including your appointment as CEO and President. I trust that our discussion will give ... Read More
Innovative Laboratory Technologies Facilitate Rapid Responses to Public Health Threats Due to Food Adulteration
Tuesday, May 26, 2015
Alex L. Brandt
It was late summer 2008 in China, and Beijing was abuzz as it prepared to host the Summer Olympic Games. However, just as the nation was gearing up to take center stage in one of the brightest moments... Read More
Techniques for Identifying Food Adulteration and Contamination
Friday, May 22, 2015
Gretchen Shearer
Adulteration and contamination are ongoing concerns in the food and beverage industry, as they can result in unsafe products and damage brand integrity. Small particulate or light filth contamination ... Read More
Thin-Layer Chromatography/Mass Spectrometry Analysis of Sample Mixtures Using a Compact Mass Spectrometer
Tuesday, May 12, 2015
Changtong Hao Nigel Sousou Daniel Eikel Jack Henion
Thin-layer chromatography (TLC) is a planar chromatographic technique used to separate the components of a mixture by employing a thin stationary phase supported by an inert backing. It can be ... Read More
Improving the Crystallization Process for Optimal Drug Development
Friday, March 28, 2014
Michael Collazo Soheila Vaezeslami Sarah Burl
Macromolecular X-ray crystallography is an important and powerful technique in drug discovery. Studying the specific interactions of a particular drug with its protein target at the atomic level can ... Read More
Evolution of Wyatt Technology Corp.
Tuesday, May 06, 2014
Robert L. Stevenson, Ph.D.
Over the last 56 years, Wyatt Technology Corp. (WTC), including the adaptation of innovations from its progenitor, Science Spectrum, has earned a reputation for developing and marketing instruments ... Read More
Focus Sharpens on Miniature Optical Spectrometers at Pittcon®
Tuesday, May 06, 2014
Matt Wilkinson
Optical spectroscopy often seems to be somewhat overlooked at Pittcon®, with much of the attention focusing on hyphenated technologies such as GC/MS or ultrahigh-performance liquid chromatography (... Read More
New Products for Gas Chromatography at Pittcon^® 2014
Tuesday, May 06, 2014
Robert L. Stevenson, Ph.D.
Pittcon® is changing rapidly. After decades where separation science including GC/MS and LC/MS dominated the meeting, a report by Dr. Matt Wilkinson in this issue demonstrates that optical ... Read More
Sample Processing at Pittcon® 2014
Tuesday, May 06, 2014
Robert L. Stevenson, Ph.D.
The tenfold increase in speed for the analytics (GC, HPLC, and SFC [supercritical fluid chromatography], all with MS) over the last decade has shifted the choke point in many workflows from analytics ... Read More
Mass Spectrometry—The Quest for Ionization Improvements: Notable New MS Products at Pittcon 2014
Tuesday, May 06, 2014
Brian Musselman
Sitting here watching March Madness reminded me of the new instrumentation presented at Pittcon® in Chicago. Not one, but two, mass spectrometer prod- ucts were awarded a Pittcon Editors’ Award, ... Read More
LIMS-BPMS Coupling: A Novel Approach for Flexible End-to-End Workflow Automation in Life Science Laboratories, Part 1
Tuesday, March 11, 2014
Kerstin Thurow Silke Holzmüller-Laue Bernd Göde
Generalized life science automation (LSA) includes all application areas of laboratory automation, i.e., health care, pharmaceutical development, chemistry, and biology. The connection of all ... Read More
Optimizing Research Success With Smarter Scientific Informatics
Monday, May 09, 2011
Frank Brown
Regardless of their area of specialization, today’s biotechnology companies want to do two things: improve the speed and success of their research efforts and lower the costs involved in doing so. Read More
Cellular Reprogramming: Opportunities and Challenges
Monday, May 09, 2011
Vi Chu Amy Noble Louise Rollins
In 2007, researchers created the first human induced pluripotent stem cells (iPS cells) by infecting skin cells with four transcription factors (Oct-4, Klf4, Sox-2, and c-Myc). Read More
A System for Individual Rare Cell Recovery and Manipulation
Monday, May 09, 2011
Frank Gannon
One of the most valuable emerging tools for prognostic indication of cancer is the detection and quantification of circulating tumor cells (CTCs). Read More
Methods to Increase Consumer Confidence in Premium Olive Oils
Tuesday, May 10, 2011
Steve Zelenak
In 2007, the U.S. Marshals Service seized 10,939 cases of extra virgin olive oil and pomace olive oil, valued at approximately $628,000, in Long Island City, NY. Read More
Micro RNA Profiling with a Multiplexed Assay
Monday, March 03, 2014
Mark Santos
From the discovery of new miRNAs to clarifying their biological roles and utility as biomarkers, micro RNA (miRNA)-based research is undergoing a period of change. Rigorous methods are therefore ... Read More