Application Notes

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FTIR-ATR Spectroscopy for Identification of Illicit Drugs Seized From Clandestine Laboratories
Thursday, November 01, 2007
Eric J. Bukowski John A. Monti
Methamphetamines and many other illicit drugs do not occur naturally; they are synthesized in clandestine laboratories across the country. Read More
Decreasing Turnaround Time of DNA Analysis by Improving Processes in the Laboratory
Monday, September 03, 2007
Steve Kemp Richard Pinchin
Forensic Science Service Ltd. (Birmingham, U.K.), trading as The Forensic Science Service® (FSS®), is a U.K. government-owned company that provides next-generation forensic science to international ... Read More
Combined Mid-IR/Near-IR Spectrometers in Materials Characterization
Monday, September 03, 2007
Jerry Sellors
When analysts are faced with the decision of selecting either mid-IR or near-IR spectroscopy for materials characterization, the decision is usually based on the analytical, sampling, and/or ... Read More
Comprehensive Laboratory Informatics: A Multilayer Approach
Monday, September 03, 2007
Simon Wood
Commercial LIMS have been available for more than 20 years and have become key elements in the laboratory informatics framework. Read More
A Novel Electrode Material That Extends the Utility of HPLC–Electrochemical Detection
Wednesday, August 01, 2007
John Waraska Ian N. Acworth
Boron-doped diamond (BDD), a working electrode material developed for use with HPLC–electrochemical detection, promises to open new areas for analysis with electrochemical detectors. Read More
A Noninvasive Method for Deep Raman Spectroscopy of Living Tissue and Powders
Wednesday, August 01, 2007
Charlotte Eliasson Pavel Matousek
Many analytical applications require fast, noninvasive characterization of deep regions of diffusely scattering (turbid) media, such as living tissue and powders, with high chemical specificity. Read More
Increasing Throughput and Lowering Detection Levels in ICP-MS Analysis Using a Microwave Digestion Quartz Rotor for Sample Preparation
Wednesday, August 01, 2007
Tim Michel Victoria Jacobs Merrill Loechner
Analytical chemists are being asked to perform trace and ultratrace metals analysis on a routine basis. Read More
DSC–Microscopy
Wednesday, August 01, 2007
Steve Sauerbrunn Michael Zemo Tom Basalik
Differential scanning calorimetry (DSC) has been the primary thermal analysis tool since its inception many decades ago. Read More
Centrifuge Rotor Selection and Maintenance
Friday, June 01, 2007
Tammy Goodman
Laboratory centrifuges are common, everyday instruments. Yet selecting the proper centrifuge and rotor system for a specific application can sometimes be a challenge. Read More
Increased Throughput in Method 8270 Analysis
Monday, January 01, 2007
William D. Goodman Frank DeLorenzo
Method 8270 is a GC-MS method created by the U.S. EPA Office of Solid Waste for the analysis of semivolatile organics by gas chromatography-mass spectrometry. Read More
Automated Chemical Ionization in GC-MS
Monday, January 01, 2007
Chris Sandy Jean-Francois Garnier Bernhard Rothweiler Fred Feyerherm Sihem Ben Mahmoud Harry F. Prest
Gas chromatography with mass spectrometric detection using chemical ionization (CI) has demonstrated great utility in a wide variety of application areas ranging from forensics to environmental to ... Read More
Dielectrophoretic Force Microscopy
Wednesday, January 19, 2005
Al M. Hilton Brian P. Lynch Garth J. Simpson
Dielectrophoresis (DEP), the force exerted on a polarizable particle in a nonuniform electric field, has been used with great success in recent years to manipulate and separate cells and biomolecules. Read More
Improved Capabilities of Noncell-Based Permeability Assays
Monday, April 10, 2006
Greg Kazan
Assays that predict passive absorption of orally administered drugs have become increasingly important in the early drug discovery process. Read More
The Future of Information Technology: Selecting a Forward- Looking LIMS Vendor
Friday, March 10, 2006
David Leitham
Most sophisticated LIMS purchasers have a well-developed methodology for evaluating which system best meets their needs. Read More
Aligning Ultrafast NMR Spectroscopy and Cold Probe Technology to Reveal the Mysteries of Protein Dynamics
Wednesday, March 01, 2006
Judit Losonczi Eriks Kupce George Gray Peter Sandor Bernhard Brutscher
The understanding of protein dynamics, the way these molecules fold to form a stable structure, interact with other molecules, or undergo changes during enzyme activity, etc., in their native ... Read More
Dynamic Light Scattering For the Noninvasive Detection of Protein Aggregation
Wednesday, February 01, 2006
Bernard Lorber
Protein homogeneity is an important issue in many fields of research, be it the characterization of newly isolated molecules, the identification of crystallizable samples, or the preparation of ... Read More
Managing Laboratory Maintenance
Tuesday, February 07, 2006
L. Wayne Collins
Other than personnel-related costs, maintenance is generally the most expensive item in the laboratory operating budget. Read More
Single-Step Purification of Lactase From a New Isolate of L. acidophilus
Wednesday, February 01, 2006
Sameer K. Akolkar Smita S. Lele
Lactase (ß-D-galactohydrolase EC 3.2.1.23) is widely distributed in microorganisms, plants, and animals. Read More
Defragmenting Chiral Chromatography
Wednesday, February 01, 2006
Regina Valluzzi Benjamin Chaloner-Gill
Chiral molecules continue to drive growth across a number of industries as new chemistries, active ingredients, and products are developed and commercialized. Read More
Nitrogen Generation in an Environmental Testing Laboratory
Thursday, September 07, 2006
Phillip Allison
Belmont Labs, located in Englewood, OH, is an environmental testing facility offering analytical services to clients in industry, civil/environmental engineering, and state and local governments. Read More