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Separation Science: Do We Always Need Gas Chromatography-Mass Spectrometry (GC-MS)?
Monday, October 01, 2012
Robert L. Stevenson, Ph.D.
In all too many applications of gas chromatography (GC), there is a need for supporting confirmation of a result.
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Modification of DNA in Relation to Diabetes: Identification of CMdC From Glycoxidation Reactions and Estimation of CMdC and CMdA in Fasting Human Urine
Monday, October 08, 2012
Zeenat Ara Lila
Rafida Idris
Mahtabuddin Ahmed
Kamika Manzano
Gabrielle Jenkins
Tatreka M. Polite
Miranda Williamson
The involvement of proteins in glycoxidative and lipoperoxidation reactions leads to conditions such as cataracts in lenses, atherosclerosis, and other age-related diseases.
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Culturing Cells Under Hypoxic Conditions for Biologically Relevant Results
Tuesday, October 16, 2012
Mary Kay Bates
For many decades, animal cells have been cultured in air supplemented with carbon dioxide, but new applications for cell therapies require conditions mimicking those in vivo.
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Deactivation of Metal Surfaces: Applications in Gas Chromatography (GC) for the Past 15 Years
Thursday, November 01, 2012
Jaap de Zeeuw
In 1987, Restek Corp. (Middelburg, The Netherlands) introduced a new way to deactivate metal columns, called SilcoSteel.
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2012 Light Scattering Colloquium: Advances in Nanotechnology, Protein Structures, and Biomedical Research
Wednesday, November 28, 2012
Robert L. Stevenson, Ph.D.
Light scattering provides the most effective technology to characterize large molecules and subvisible particles.
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Product Intelligence: Guide to Micromanipulators
Wednesday, November 14, 2012
Caitlin Smith
As explained in this article, micromanipulators are used in a wide variety of applications in areas as varied as electrophysiology to reproductive biology. Purchasing considerations include type of ...
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Chemicals are Back!
Friday, December 07, 2012
Robert L. Stevenson, Ph.D.
The tsunami on the business horizon is the resurrection of the American chemicals industry.
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Improving Tools for Structured Query Language (SQL)
Monday, December 10, 2012
Robert L. Stevenson, Ph.D.
Since structured query language (SQL) was introduced 40 years ago, it has evolved and mutated to become the most popular tool for managing tabular databases.
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Bioassays and Bioanalytical Method Development 2012
Monday, December 10, 2012
Robert L. Stevenson, Ph.D.
The 8th Annual Bioassays and Bioanalytical Method Development conference, organized by the Institute for International Research (IIR) in Sarasota, FL, attracted more than 100 scientists to the classic...
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World Genome Data Analysis Summit 2012: Big Data, Big Problems, and Thoughtful Solutions
Wednesday, December 12, 2012
Robert L. Stevenson, Ph.D.
The World Genome Data Analysis Summit attracted about 70 scientists and engineers to the Monaco Hotel in San Francisco, CA, November 27–29 to talk shop on DNA data.
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Technical Innovations In Liquid Chromatography-Mass Spectrometry
Wednesday, December 12, 2012
Robert L. Stevenson, Ph.D.
Innovation is a respected attribute that many companies claim as a core business strategy. The pace of innovation spurred by technology such as smartphones, tablet PCs, and high-speed internet has ...
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Reducing DNA Sample Backlogs and Protecting Chain-of-Custody in the Forensic Laboratory
Monday, December 24, 2012
Laurent Baron
Bobby Chavli
Lois Tack
Annette Summers
For years, forensic laboratories in the U.S. have struggled to reduce DNA sample processing backlogs and human errors, both of which hinder timely and reliable criminal convictions.
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Neutron Crystallography Contributes to Drug Design
Monday, January 07, 2013
Zoe Fisher
Carbonic anhydrases are a large group of enzymes that are expressed in humans. Carbonic anhydrase (CA) catalyzes the reversible hydration of CO2 to make bicarbonate and a proton. As such, this enzyme ...
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Fast, Reproducible Quantitation of dsDNA and Protein With Microvolume UV-VIS Spectrophotometry
Monday, January 28, 2013
Andrew Shaff
Jeff Head
John Kinyunjui
Mark Talbott
Procedures for nucleic acid and protein quantitation have come a long way in the last three decades. In fact, the analysis of small samples (1–4 µL) is now routine in many life science laboratories.
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High-Content Analysis (HCA 2013): 3-D Reduces the Gap Between In Vitro and In Vivo
Tuesday, February 05, 2013
Robert L. Stevenson, Ph.D.
The 10th High-Content Analysis meeting attracted about 300 scientists to San Francisco’s Fairmont Hotel (January 8–11, 2013). A Venn diagram of attendees would certainly include overlapping circles ...
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Automated Assays and More at SLAS 2013 and HCA 2013
Wednesday, February 06, 2013
Robert L. Stevenson, Ph.D.
The second annual meeting of the Society for Laboratory Automation and Screening (SLAS 2013), held January 12–16, attracted 3800 scientists and engineers to the Gaylord Hotel in Orlando, FL for an ...
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Focus on Liquid Handling and 3-D Imaging at SLAS 2013
Friday, February 08, 2013
Robert L. Stevenson, Ph.D.
Most commonly, laboratory automation involves a few hundred wells run for a specific purpose. SLAS 2013, the meeting of the Society for Laboratory Automation and Screening, was held at the Gaylord ...
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Automated Botulinum Neurotoxin Detection
Monday, February 25, 2013
Karine Bagramyan
Aneela Reddy
Dobrin Nedelkov
Markus Kalkum
Botulinum neurotoxin (BoNT) is undoubtedly the most potent biological toxin known. Intravenously injected it could paralyze and kill a human being at a dose of just 1.2 ng BoNT per kg body weight.
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Field-Portable Analyzers Based on Cavity-Enhanced Laser Absorption Spectrometry
Friday, January 18, 2013
Manish Gupta
J. Brian Leen
Accurate measurements of greenhouse gases and pollutants are critical to emerging environmental regulations and industrial compliance monitoring. Until recently, many of these measurements involved ...
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Review of U.S. EPA Methods for Perchlorate Using Suppressed Conductivity Detection
Tuesday, January 22, 2013
Jeff Rohrer
Richard Jack
Brian De Borba
Lillian Chen
Perchlorate is identified as an environmental contaminant found in drinking, ground, and surface waters. The origins of perchlorate are both natural and anthropogenic. In its natural origin, ...
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