Don Weldon

Screening Live Cells Using RNA Detection Probes
Friday, June 12, 2015
RNA expression is the next frontier in biomarker development because it offers an indication of cellular intent. mRNA expression, in particular, can show how a cell responds to its environment or ... read more
Single-Cell RNA Detection to Identify Cell Subpopulations in Heterogeneous Mixtures
Tuesday, March 25, 2014
Traditional RNA detection methods, which analyze RNA levels in lysed, permeabilized, or fixed cell samples, make it challenging to understand the role of one gene in the context of a tissue, organ, or... read more
Identification of Cancer Stem Cells Within Mixed Populations Using Live Cell RNA Detection
Thursday, January 09, 2014
Despite the ubiquity of studies measuring mRNA and miRNA levels, many current techniques require cell lysis and are enormously disruptive to the cells being studied. read more
Detection of siRNA-Mediated Gene Modulation Using RNA Detection Probes
Monday, May 20, 2013
To study the function of genes and biological pathways, researchers often use techniques such as RNA interference (RNAi) to modify gene expression. In RNAi experiments, it is important to determine ... read more