SOUTH SAN FRANCISCO, Calif. – October 18, 2022 – Twist Bioscience Corporation (NASDAQ: TWST), a company enabling customers to succeed through its offering of high-quality synthetic DNA using its silicon platform, today announced the launch of the Twist Human Sample ID Kit to provide researchers with a solution to track samples throughout the lab workflow. The Twist Human Sample ID Kit can be easily integrated into Twist NGS workflows and enables tracking from whole blood or purified genomic DNA to ensure sample identification throughout the lab workflow, offering robust coverage and high confidence in the detection of genetic variations to distinguish between samples.
Laboratories that offer next-generation sequencing (NGS) services receive a high volume of samples with an expectation of fast turnaround time and accurate reporting. To keep up with the high volume, the labs run tests with complex workflows for multiple samples in the same batch. This can lead to sample mix-ups, which often requires re-runs or, if not identified, results in misinterpretation of data for critical samples. Current safeguards against misidentification are not always integrable with NGS workflows or may not enable tracking samples from whole blood. Sample ID allows researchers to identify the sample at the beginning of the NGS workflow to eliminate misidentification or labeling two different samples as identical. Sample ID also offers high discrimination and is able to distinguish between samples that are genetically related, such as those from a family trio.
“The Twist Human Sample ID Kit enables customers to run tests with confidence by reducing sample mix-ups that could result in data misinformation and re-sequencing down the line, allowing them to focus on their research,” said Emily M. Leproust, Ph.D., CEO and co-founder of Twist Bioscience. “As our customers conduct increasingly complex research to enable precision medicine, we continue to develop and adapt our offerings to fit their needs. This end-to-end workflow solution adds to our portfolio of NGS products that we believe will expand our market share as we seek to own the space between the sample and the sequencer.”
Twist Human Sample ID Kit Workflow
The Twist Human Sample ID Kit prepares sequence-ready genotyping libraries in a streamlined workflow. It is designed to be used in combination with the Twist Exome 2.0 panel and custom panels complemented with the Sample ID content. The workflow requires a single PCR reaction, with 2 μl of whole blood (or 10 ng of purified DNA), followed by standard Twist NGS library preparation. The Twist Human Sample ID Kit enables labs to independently verify the correct results are attributed to the right sample with as little as five minutes of extra hands-on time.
About Twist Bioscience Corporation
Twist Bioscience is a leading and rapidly growing synthetic biology and genomics company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The core of the platform is a proprietary technology that pioneers a new method of manufacturing synthetic DNA by “writing” DNA on a silicon chip. Twist is leveraging its unique technology to manufacture a broad range of synthetic DNA-based products, including synthetic genes, tools for next-generation sequencing (NGS) preparation, and antibody libraries for drug discovery and development. Twist is also pursuing longer-term opportunities in digital data storage in DNA and biologics drug discovery. Twist makes products for use across many industries including healthcare, industrial chemicals, agriculture and academic research.