Scientists Identify Genetic Mutation That Leads to Antifungal Drug Resistance

Aspergillosis results in severe infections, and resistance to antifungal drug regimens makes these infections increasingly difficult to treat.

Researchers from Swansea University, the University of Tennessee, and the University of Texas investigated resistance to the triazole class of antifungal drugs used to treat aspergillosis. They were able to identify a previously uncharacterized genetic mutation in clinical isolates that leads to resistance.

It is hoped that a better understanding of how the fungus becomes resistant to drugs will lead to the design of improved treatment strategies.

  • <<
  • >>