The X-MAN human cell line collection (http://info.horizondiscovery.com/xman/?utm_source=Horizon%20Main%20List&utm_campaign=0f8db6ee99-XMANDiseaseModelsIndustry2_23_2015&utm_medium=email&utm_term=0_324b66abf7-0f8db6ee99-243797945) from Horizon Discovery (Cambridge, U.K.) contains over 1400 diploid and haploid cell lines containing defined genomic modifications. The collection is a useful resource for the characterization of genes and their role in disease biology and drug responses. The cell lines are supplied as isogenic pairs (mutant vs control) and are available individually or as extensive gene family and signaling pathway panels