Article Archives

Over the past 20 years, liquid chromatography-multiple reaction monitoring-mass spectrometry (LC-MRM-MS) has become the primary tool for the bioanalysis of drugs and their metabolites in physiological... read more

Ion chromatography (IC) with conductivity detection has been used successfully to determine anionic and cationic substances as well as polar compounds such as amines and organic acids. However, in ... read more

The introduction of Quality by Design, a systematic approach to product and process design and development, has shifted the paradigm in HPLC methods development from a retrospective approach to a ... read more

Phosphate-buffered saline (PBS), a buffer solution commonly used in many biological research fields, contains monobasic potassium phosphate, sodium chloride, and dibasic sodium phosphate. read more

Over the last decade, monolith technology has progressed from a promising approach conceived by Fréchet, Švec, Huber, and others to a well-developed separation tool. read more

During any extract ion process, interferences can also be extracted along with desired analytes. read more

Testing hair for drugs of abuse has been practiced for over 50 years, due in large part to the ability to detect drug use over a longer period of time, as compared to other biological matrices, ... read more

The deposited salts and brine from salt lakes are important industrial resources for many kinds of salts, such as edible salt, potassium, boron, lithium, and a few heavy metals. read more

Procedures for nucleic acid and protein quantitation have come a long way in the last three decades. In fact, the analysis of small samples (1–4 µL) is now routine in many life science laboratories. read more