Tuesday, February 26, 2013
Technical Article
Robert L. Stevenson
Integrated R&D Informatics and Knowledge Management (I&KM) was the title of one of the 15 programs spread over three days at the 20th Molecular Med Tri-Con held February 13–15 at the Moscone Center in...
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Tuesday, October 02, 2012
Application Note
Michael Boruta
This article focuses on a means of capturing spectrum-to-structure correlations for Raman and infrared spectra. It discusses methods that can be used to obtain, archive, and retrieve this knowledge so...
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Application Note
Juergen Schober, Jim Vecchio, John Paul Cerroti
The measurement of parameters such as oil, fat, and moisture content is important to help define the nutritional value and product quality for many foodstuffs and agriculture products.
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Wednesday, February 01, 2012
Technical Article
Philip Keyes, Michael Messinger, Gonzalo Hernandez
The pharmaceutical industry depends on testing and evaluation of novel compounds in a wide range of chemical space to feed its pipelines.
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Tuesday, January 10, 2012
Technical Article
Philip Keyes, Michael Messinger, Gonzalo Hernandez
The pharmaceutical industry has always relied on testing and evaluating novel compounds in a wide range of chemical space to feed its pipelines.
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Saturday, October 01, 2011
Technical Article
Robert L. Stevenson
Society has invested tens of billions
of dollars in the last two
decades to sequence the human
genome and look for biomarkers
to fight disease and guide therapy.
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Thursday, September 01, 2011
Application Note
Pat Kriwoy, Peter Froehlich
Nuclear magnetic resonance (NMR) spectroscopy is an extremely important tool in the elucidation of molecular
structure and is commonly used to obtain
information about the interaction between ...
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Thursday, August 25, 2011
Technical Article
Habil J. Sabine Becker, Meike Hamester
The Analytical BrainMet (Bioimaging of Metals in Brain and Metallomics) Centre at the Forschungszentrum Jülich, Germany, has developed novel mass spectrometry imaging (MSI) techniques using laser ...
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Application Note
Induka Abeysena, Rob Darrington
Lyophilization is often the preferred
method of sample drying because a high level of dryness is achieved with low residual solvent levels, and because of the light, powdery, “fluffy” finish of the ...
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Technical Article
Vincent W. Caruso, Edward C. Brown, John P. Kay, Michael A. Mancini, James A. Westra, Philip Keyes
Safe solvent management and
storage are significant concerns
in the pharmaceutical industry,
particularly when purification
systems are run unattended and are
supplied by large volumes of organic...
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Technical Article
George M. Frame II, Eileen M. Skelly Frame
Of the 979 exhibitors at Pittcon®
2011, held March 13–18 in
Atlanta, GA, 115 were first-time
exhibitors, and more than 200
identified themselves as having something to do with spectroscopy, from ...
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Technical Article
Christopher J. White, Colin T. Elliott, James R. White
Recent years have seen a dramatic upsurge in the availability of miniaturized sensing technologies.
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Tuesday, February 01, 2011
Technical Article
Jia Luo, Quanyi Wang, Yiwen Zhang, Hang Song, Shun Yao
As a common intermediate in the synthesis of numerous pharmaceuticals, a-bromobutyric acid displays chirality at the carbon bound to the bromine.
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Thursday, September 30, 2010
Technical Article
Mao Peng, Hui Wu, Lijiao Sheng, Gongwu Song, Jiangang Zhou
In recent years, Gemini surfactants have emerged as promising surface active agents.
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Saturday, November 01, 2008
Technical Article
C. David Carr, Robert L. Stevenson
Historically, the life sciences have been qualitative in nature, seeking to identify but seldom understand quantitatively.
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Monday, September 01, 2008
Technical Article
James A. Laramée, H. Dupont Durst, Theresa R. Connell, J. Michael Nilles
Analysis of low-volatility, condensed- phase chemicals on surfaces has been an extremely difficult and long-standing objective in environmental monitoring.
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Saturday, November 03, 2007
Technical Article
Daniel L. Sweeney
The relative ease of obtaining accurate-mass fragmentation
data on modern LC-MS instruments,
faster computers, and the availability of large molecular structure databases have recently made it ...
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Application Note
Allan Matte, Miroslaw Cygler
Improving protein solution behavior is critical in the field of structural biology since it impacts protein
crystallization and the ability to determine protein structures by solution nuclear ...
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Wednesday, March 01, 2006
Application Note
Judit Losonczi, George Gray, Peter Sandor, Bernhard Brutscher, Eriks Kupce
The understanding of protein dynamics,
the way these molecules fold to
form a stable structure, interact with
other molecules, or undergo changes
during enzyme activity, etc., in their
native ...
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Friday, February 03, 2006
Technical Article
Verna Frasca
Many soluble proteins misfold and form insoluble amyloid fibrils. This process occurs in many neurodegenerative disorders, such as Alzheimer’s disease, amyotrophic lateral sclerosis, Parkinson’s ...
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