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  • Improving the Crystallization Process for Optimal  Drug Development

    Improving the Crystallization Process for Optimal Drug Development

    Friday, March 28, 2014
    Application Note
    Michael Collazo, Soheila Vaezeslami, Sarah Burl
    Macromolecular X-ray crystallography is an important and powerful technique in drug discovery. Studying the specific interactions of a particular drug with its protein target at the atomic level can ... read more
  • Pittcon 2013®: Developments in Liquid Chromatography

    Pittcon 2013®: Developments in Liquid Chromatography

    Monday, May 13, 2013
    Technical Article
    Robert L. Stevenson
    The first commercial liquid chromatograph was probably an amino acid analyzer. These ion exchange chromatographs were so specialized that they had almost no impact on chemical analysis outside of ... read more
  • What’s New in Optical Spectroscopy at Pittcon® 2013?

    What’s New in Optical Spectroscopy at Pittcon® 2013?

    Friday, May 10, 2013
    Technical Article
    Mark Fisher
    Soon after the first spectrophotometer was built, the challenge of improving it began. How could we make spectrophotometers better? Could we make them smaller, faster, or perhaps improve the ... read more
  • Recent Developments in Sulfur Analysis

    Recent Developments in Sulfur Analysis

    Thursday, January 17, 2013
    Application Note
    Scott Fess
    Environmental concerns to limit and minimize sulfur in crude oil and petroleum fuels are continuing to spread to many regions of the world, requiring new standard test methods and modern ... read more
  • Neutron Crystallography Contributes to Drug Design

    Neutron Crystallography Contributes to Drug Design

    Monday, January 07, 2013
    Technical Article
    Zoe Fisher
    Carbonic anhydrases are a large group of enzymes that are expressed in humans. Carbonic anhydrase (CA) catalyzes the reversible hydration of CO2 to make bicarbonate and a proton. As such, this enzyme ... read more
  • Pittcon® 2012 Roundup of Spectroscopy and Mass Spectrometry

    Pittcon® 2012 Roundup of Spectroscopy and Mass Spectrometry

    Monday, May 07, 2012
    Technical Article
    Jeffrey M. Perkel
    This past March, some 15,754 people from 90 countries descended on Orlando, Florida, for the annual Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy (Pittcon®). read more
  • New Products at Pittcon® 2011

    New Products at Pittcon® 2011

    Thursday, March 10, 2011
    Application Note
    Jeanely Hunt, MS, MBA
    The following includes some of the latest advances in laboratory instrumentation debuting at Pittcon® 2011. read more
  • Reintroducing Countercurrent Chromatography to the Chemist

    Reintroducing Countercurrent Chromatography to the Chemist

    Friday, October 24, 2008
    Application Note
    David Keay, Philip Wood
    Ever since chemists began using separating funnels to isolate compounds by partitioning, they have understood the potential benefits of liquid/liquid chromatography, known today as countercurrent ... read more
  • Performance Evaluation of an Integrated Analytical HPLC

    Performance Evaluation of an Integrated Analytical HPLC

    Thursday, July 10, 2008
    Application Note
    Glyn Russell, Phuong Truong, Lindsay Buck, Frankie Button
    As a routine analytical tool in the laboratory, there are many important performance requirements such as precision, reproducibility, and sensitivity for an analytical HPLC to achieve satisfactory use... read more
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