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  • Electronic Pipetting: The Call for Innovation

    Electronic Pipetting: The Call for Innovation

    Thursday, February 27, 2014
    Application Note
    Paula Heimler
    Take a close look around most laboratories and you will find an old, barely used fixture. No one knows who ordered it or who it belongs to. It is yellowed, dusty, and top heavy, with a small keyboard ... read more
  • Bioassays and Bioanalytical Method Development 2013

    Bioassays and Bioanalytical Method Development 2013

    Tuesday, November 12, 2013
    Technical Article
    Robert L. Stevenson
    Biotherapeutics are generally large molecules with a heterogeneous complex structure that is directly related to their ability to modulate biological reactions. This precludes defining a meaningful ... read more
  • Fast, Efficient Antibody Biotinylation for Cleaner Immunodetection Assays

    Fast, Efficient Antibody Biotinylation for Cleaner Immunodetection Assays

    Friday, June 07, 2013
    Application Note
    Amedeo Cappione, Masaharu Mabuchi, David Briggs, Timothy Nadler
    Many protein detection methods, including Western blotting, flow cytometry, ELISA, and immunohistochemistry, require the use of target-specific probes, such as antibodies, that are detected via two-... read more
  • Putting the “More” in Morphology: Part 1

    Putting the “More” in Morphology: Part 1

    Wednesday, April 10, 2013
    Technical Article
    Barbara Foster
    Segmentation, the ability to define the unique features in a region of interest, has always been the greatest challenge in image analysis and quantitation. A new suite of tools, available from ... read more
  • An Ultrasensitive Immunoassay Detection System for Biomarkers Utilizing Raman Scattering Methods

    An Ultrasensitive Immunoassay Detection System for Biomarkers Utilizing Raman Scattering Methods

    Wednesday, October 31, 2012
    Technical Article
    Samar Kundu, Charles Ginsburgh, Sandra Lynch, Neal Siegel
    Detection of low levels of biomarkers utilizing enzyme linked immunosorbent assay (ELISA) technology is demonstrated through the use of Raman scattering techniques and a convertible substrate for ... read more
  • Multicapillary Columns for Chromatography

    Multicapillary Columns for Chromatography

    Tuesday, March 01, 2005
    Technical Article
    Yuri P. Belov, Marina M. Ulyanova, Vladimir N. Sidelnikov
    The principles and theory of high-speed capillary chromatography have been known since the 1960s. To realize the maximum speed capabilities, it is necessary to use capillaries with a diameter of ... read more
  • Rapid Testing of Toxic Chemicals

    Rapid Testing of Toxic Chemicals

    Tuesday, March 01, 2005
    Application Note
    Nathalie Boucher, Lucie Lorrain, Marie-Eve Rouette, Elisabeth Perron, Nancy Déziel, Louis Tessier, François Bellemare
    The measurement of chlorophyll fluorescent signals from photosynthetic enzyme complexes (PEC) has becomeone of the most powerful indicators for ecophysiologists. read more
  • Miniaturized FTIR for Maximized Productivity

    Miniaturized FTIR for Maximized Productivity

    Tuesday, March 01, 2005
    Application Note
    Ken Fredeen, John S. Seelenbinder, Mark L. Norman
    In today’s fast-paced business environment, many companies are under pressure to improve their productivity. This is especially true in the pharmaceutical industry, where reducing time-to-market ... read more
  • LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    LC-MS With Simultaneous Electrospray and Atmospheric Pressure Chemical Ionization

    Tuesday, March 01, 2005
    Technical Article
    Wayne P. Duncan, Patrick D. Perkins
    Today, liquid chromatography-mass spectrometry with electrospray ionization (LC-ESI-MS) is increasingly being used as the technique of choice for high-throughput pharmaceutical analysis. read more
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