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  • Improving the Crystallization Process for Optimal Drug Development

    Friday, March 28, 2014
    Application Note
    Michael Collazo Soheila Vaezeslami Sarah Burl
    Macromolecular X-ray crystallography is an important and powerful technique in drug discovery. Studying the specific interactions of a particular drug with its protein target at the atomic level can ... read more
  • Neutron Crystallography Contributes to Drug Design

    Monday, January 07, 2013
    Technical Article
    Zoe Fisher
    Carbonic anhydrases are a large group of enzymes that are expressed in humans. Carbonic anhydrase (CA) catalyzes the reversible hydration of CO2 to make bicarbonate and a proton. As such, this enzyme ... read more
  • Product Intelligence: Homogenizers Buyers’ Guide

    Monday, August 06, 2012
    Technical Article
    T. Keith Brock
    The mechanical, pressure, and ultrasonic homogenizer represent the three primary methods used to blend, mix, disrupt, emulsify, disperse, and stir samples. This article explains the role of ... read more
  • Increased Throughput in Method 8270 Analysis

    Monday, January 01, 2007
    Application Note
    William D. Goodman Frank DeLorenzo
    Method 8270 is a GC-MS method created by the U.S. EPA Office of Solid Waste for the analysis of semivolatile organics by gas chromatography-mass spectrometry. read more
  • Automated Chemical Ionization in GC-MS

    Monday, January 01, 2007
    Application Note
    Chris Sandy Jean-Francois Garnier Bernhard Rothweiler Fred Feyerherm Sihem Ben Mahmoud Harry F. Prest
    Gas chromatography with mass spectrometric detection using chemical ionization (CI) has demonstrated great utility in a wide variety of application areas ranging from forensics to environmental to ... read more
  • Increasing Application of X-Ray Powder Diffraction in the Pharmaceutical Industry

    Wednesday, June 01, 2005
    Application Note
    Brian Litteer Detlef Beckers
    X-ray powder diffraction has recently been propelled to the forefront as an analytical tool in the pharmaceutical industry for a wide range of applications. read more
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