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Date Published
Title
Evaluating Candidate Lead Compounds by Rapid Analysis of Drug Interactions with Human Serum Albumin
Tuesday, April 22, 2008
Vered Bronner
Oded Nahshol
Tsafrir Bravman
Human serum albumin (HSA) plays a fundamental role in the transport of drugs, metabolites, and endogenous ligands. Binding to HSA controls the free, active concentration of a drug; provides a ...
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Light Engines for the Life Sciences
Thursday, September 04, 2008
Arlie R. Conner
Claudia B. Jaffe
Steven M. Jaffe
Life science instruments present unique challenges to suppliers of light-generation equipment: Inexpensive, high-intensity, uniform, monochromatic light across a broad UV-VIS-IR spectrum is required...
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Multidetection Microplate Readers: Filter-Based, Monochromator-Based. . .or Both?
Friday, June 01, 2007
Xavier Amouretti
The appeal of multidetection microplate readers is easy to understand: they combine multiple measurement technologies such as absorbance, fluorescence,and luminescence into one compact instrument.
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When Analyzing Cancer at the Molecular Level, Microliters Matter
Friday, November 30, 2007
This year, more than 1.4 million Americans will be diagnosed with cancer. An extremely complex disease family, cancer affects all types of people, from all nationalities and genetic make-ups.
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Improved Column Chromatography Performance Using Arginine
Thursday, February 01, 2007
Daisuke Ejima
Kouhei Tsumoto
Tsutomu Arakawa
Protein purification and analysis using column chromatography is facing new challenges because of increasing demands in the proteomic and biotechnology fields.
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A Charged Aerosol Detector That Reduces Vaccine Development Time
Thursday, March 01, 2007
Jerry Fireman
Darrick Carter
Mary Wallace
The Infectious Disease Research Institute (IDRI, Seattle, WA) is a not-for-profit corporation that has developed the first defined vaccine for leishmaniasis, which is now in clinical trials, in ...
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Selection and Development of Bulk Liquid Dispensing Technology
Saturday, September 01, 2007
Jason Greene
A vast majority of research is dependent on the transfer of a measured volume of liquid from one vessel to another, such as from a bulk container to a microplate.
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New Technologies in Human Genetic Analysis
Wednesday, April 04, 2007
Mark E. Samuels
Brent Higgins
Sylvie Provost
Julien Marcadier
Christian Blouin
Sharen Bowman
Marie-Pierre Dubé
Human genetics has benefited in the last decade from spectacular technological advances in DNA analysis.
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The LED Light Source: A Major Advance in Fluorescence Microscopy
Wednesday, October 10, 2007
Becky Hohman
Fluorescence microscopy requires an intense light source at the specific wavelength that will excite fluorescent dyes and proteins.
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Attomole Quantitative Chemiluminescence for Molecular Diagnostics
Monday, January 01, 2007
Aaron Ho
Jian Tajbakhsh
The study and use of bioluminescence and chemiluminescence have increased dramatically in recent years.
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Advances in Microscale Protein Fractionation and Analysis
Monday, January 01, 2007
Julie S. Hey
Fractionation is an essential step in the identification of proteins and their subsequent structural characterization.
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Ultrasensitive Measurement of Protein and Nucleic Acid Biomarkers for Earlier Disease Detection and More Effective Therapies
Friday, January 19, 2007
Gregory Shipp
It is a universal fact substantiated by decades of biopharmaceutical research: the earlier a disease is detected, the more likely treatments will be effective in alleviating or stabilizing the disease...
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Calorimetry: Getting the Winning Combination
Wednesday, July 18, 2007
Ed Sullivan
Ultrasensitive calorimetric instruments for measuring very small heats of reaction at constant temperature (isothermal titration calorimetry [ITC]) and small heat effects induced by temperature (...
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Pipets and Ergonomics: What Matters Most
Monday, October 01, 2007
Craig Weiss
The handheld pipet is perhaps the most ubiquitous piece of equipment in any laboratory.
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The Search for Promising Viral Targets in Drug Discovery
Wednesday, August 08, 2007
Colleen B. Jonsson
Lucile White
James Noah
William Severson
Marintha Heil
In the past decade we have seen advances in laboratory automation and in assays used to assess biological endpoints.
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A Novel Mechanism for Controlling and Monitoring Real-Time Pipet Information in a Manual System
Thursday, September 13, 2007
Jim Petrek
The modern manual pipet has been a laboratory workhorse for several decades, providing researchers with a convenient tool to transfer liquids from one vessel to another with high levels of confidence ...
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Bioassays 2011
Thursday, June 23, 2011
Robert L. Stevenson, Ph.D.
During the last decade, tremendous strides have been made in proteomics and genomics.
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Seventh Annual Semantic Technology Conference (SemTech 2011): Natural Language Processing Catches up to Large-Scale Integration
Thursday, June 23, 2011
Robert L. Stevenson, Ph.D.
In 2009, when I attended the Semantic Technology Conference in San Jose, CA, the meeting was a mixture of software developers and applications reports. Many were from scientists seeking to improve ...
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Impact of HTS on Multidetection Microplate Readers and Benefits For Life Science Research Laboratories
Tuesday, August 01, 2006
Xavier Amouretti
The basic concept behind high-throughput screening (HTS) is a numbers game: If one has the technical ability to test thousands upon thousands of potential drug compounds against a specific target, it ...
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Protein Stability Monitored by Fourier Transform Infrared Spectrometry
Thursday, June 01, 2006
Michael S. Bradley
Degradation of proteins during storage or processing is a major concern in both manufacturing and research.
read more
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