June 19, 2012 - A new guide entitled 'Top Ten Tips for Gene Silencing & Delivery' is available from AMSBIO. Drawing upon extensive experience of gene silencing techniques the new guide is aimed at assisting research scientists using or planning to use gene knockdown as a method of revealing the function of genes in biological processes.
The informative guide provides expert hints and tips on topics including: How to determine the RNAi tools best suited to your application ; The importance of performing appropriate positive and negative controls ; Precautions to minimise exposure to RNases ; The benefits of using transfection reagents optimised for siRNA delivery ; How to obtain optimal transfection efficiency ; saving time with validated siRNA sequences ; The importance in confirming that your siRNA sequence is unique as well as How to determine the amount of siRNA required to effectively silence a given gene.
Gene silencing through the use of siRNA has become a primary tool for characterizing gene involvement in disease states and interactive pathways, there are several methods for preparing and delivering siRNA. AMSBIO can offer a variety of tools and services including products for generating siRNA, validated siRNA expression vectors and oligo sets sets, ready-to-use and custom Lentivirus particles and tailored siRNA specific transfection reagents.
For a copy of this new guide please visit http://www.amsbio.com/Gene-Silencing-Method-Troubleshooting.aspx or contact AMSBIO on +44-1235-828200 / +1-800-987-0985
Founded in 1987, AMS Biotechnology (AMSBIO) is recognised as a leading international provider of unique, innovative products & custom services for life sciences research. The AMSBIO range includes over 23,000 polyclonal & monoclonal antibodies, peptides, recombinant proteins, extracellular matrix, molecular detection reagents, & tissue DNA, RNA, protein & microarray products. Key research areas include: apoptosis, cell invasion & migration, cell signaling, DNA damage, 3D culture, electrophoresis, glycobiology, post-translational modification & stem cell biology.
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