February 2011
Volume 43, Number 2
The microwave reactor described in this issue finds application in numerous areas of microwave chemistry. Many applications can also be served with the hyphenated UHPLC super critical extraction system described in an article on the analysis of piperine in peppers.
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Table of Contents
Penny. R Gardner
Tuesday, February 01, 2011
We are very excited for Pittcon
® 2011 to be back in Atlanta, GA, March 13–18, at the Georgia World Congress Center.
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Jia Luo, Quanyi Wang, Yiwen Zhang, Hang Song, Shun Yao
Tuesday, February 01, 2011
As a common intermediate in the synthesis of numerous pharmaceuticals, a-bromobutyric acid displays chirality at the carbon bound to the bromine.
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Alexander Stadler
Tuesday, February 01, 2011
In the R&D laboratories of universities
and the pharmaceutical industry, microwave synthesis is becoming increasingly popular.
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Rohan A. Thakur, Mike Koleto
Tuesday, February 01, 2011
It is essential to eliminate poor drug
candidates as early as possible in the drug development process. Unfavorable pharmacokinetic (PK) properties have frequently been the reason for failure of new ...
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Takayuki Yamaguchi, Kazutoshi Kamezawa, Keijin Iwaya, Yasuyo Sato, Toshihiko Miyaji, Masao Bounoshita, David J. Tognarelli, Muneo Saito
Tuesday, February 01, 2011
Ultrahigh-performance liquid chromatography (UHPLC) is a separation technique that utilizes columns packed with microparticles (<2 µm in diameter), as provided by the xtreme liquid chromatography (x-lc™) system (jasco corp., tokyo, japan) µm="" in="" diameter),="" as="" provided="" by="" the="" xtreme="" liquid="" chromatography="" (x-lc™)="" system="" (jasco="" corp.,="" tokyo,="">...
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Stephen Wren, Jim Lenke
Tuesday, February 01, 2011
The performance of solid pharmaceutical products is normally assessed using the pharmacopeial in vitro dissolution test.
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Jaap de Zeeuw, Ron Stricek, Gary Stidsen
Tuesday, February 01, 2011
To analyze basic compounds at nanogram levels using gas chromatography, a basic surface modification is often required to reduce the impact of the acidic fused silica.
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Stephen J. Mangum, Kenneth R. Neubauer
Tuesday, February 01, 2011
Heavy metal exposure of a population
has been a long-standing health concern.
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Keren Hulkower, Joanne Franklin, David Onley, Paul Wylie
Tuesday, February 01, 2011
Cancer invasion from a primary tumor site is one of the critical factors in disease prognosis, and together with metastasis is the major cause of morbidity and mortality.
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Irmgard Suominen, Sami Koivisto
Tuesday, February 01, 2011
Handheld pipets are commonplace in any laboratory and are used in the vast majority of applications.
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